Pa. gov: 2-year Sandusky investigation necessary

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lesotho a wrinkle in time

ScienceDaily: Biochemistry News

http://www.sciencedaily.com/news/matter_energy/biochemistry/ Read the latest research in biochemistry -- protein structure and function, RNA and DNA, enzymes and biosynthesis and more biochemistry news.en-usMon, 18 Jun 2012 18:05:01 EDTMon, 18 Jun 2012 18:05:01 EDT60http://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/matter_energy/biochemistry/ For more science articles, visit ScienceDaily.http://www.sciencedaily.com/releases/2012/06/120618153427.htm Scientists are racing to sequence DNA faster and cheaper than ever by passing strands of the genetic material through molecule-sized pores. Now, scientists have adapted this ?nanopore? method to find DNA damage that can lead to mutations and disease.Mon, 18 Jun 2012 15:34:34 EDThttp://www.sciencedaily.com/releases/2012/06/120618153427.htmhttp://www.sciencedaily.com/releases/2012/06/120618111830.htm Overturning two long-held misconceptions about oil production in algae, scientists show that ramping up the microbes' overall metabolism by feeding them more carbon increases oil production as the organisms continue to grow. The findings may point to new ways to turn photosynthetic green algae into tiny "green factories" for producing raw materials for alternative fuels.Mon, 18 Jun 2012 11:18:18 EDThttp://www.sciencedaily.com/releases/2012/06/120618111830.htmhttp://www.sciencedaily.com/releases/2012/06/120616145535.htm The design of a nature-inspired material that can make energy-storing hydrogen gas has gone holistic. Usually, tweaking the design of this particular catalyst -- a work in progress for cheaper, better fuel cells -- results in either faster or more energy efficient production but not both. Now, researchers have found a condition that creates hydrogen faster without a loss in efficiency.Sat, 16 Jun 2012 14:55:55 EDThttp://www.sciencedaily.com/releases/2012/06/120616145535.htmhttp://www.sciencedaily.com/releases/2012/06/120615204741.htm Researchers have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow.Fri, 15 Jun 2012 20:47:47 EDThttp://www.sciencedaily.com/releases/2012/06/120615204741.htmhttp://www.sciencedaily.com/releases/2012/06/120613153331.htm A powerful color-based imaging technique is making the jump from remote sensing to the operating room. Scientists are working to ensure it performs as well when spotting cancer cells in the body as it does with oil spills in the ocean.Wed, 13 Jun 2012 15:33:33 EDThttp://www.sciencedaily.com/releases/2012/06/120613153331.htmhttp://www.sciencedaily.com/releases/2012/06/120613133341.htm In the not-too-distant future, scientists may be able to use DNA to grow their own specialized materials, thanks to the concept of directed evolution. Scientists have, for the first time, used genetic engineering and molecular evolution to develop the enzymatic synthesis of a semiconductor.Wed, 13 Jun 2012 13:33:33 EDThttp://www.sciencedaily.com/releases/2012/06/120613133341.htmhttp://www.sciencedaily.com/releases/2012/06/120613133150.htm An implantable fuel cell could power neural prosthetics that help patients regain control of limbs. Engineers have developed a fuel cell that runs on the same sugar that powers human cells: glucose. This glucose fuel cell could be used to drive highly efficient brain implants of the future, which could help paralyzed patients move their arms and legs again.Wed, 13 Jun 2012 13:31:31 EDThttp://www.sciencedaily.com/releases/2012/06/120613133150.htmhttp://www.sciencedaily.com/releases/2012/06/120613102130.htm A scientist may be onto an ocean of discovery because of his research into a little sea creature called the mantis shrimp. The research is likely to lead to making ceramics -- today's preferred material for medical implants and military body armour -- many times stronger. The mantis shrimp's can shatter aquarium glass and crab shells alike.Wed, 13 Jun 2012 10:21:21 EDThttp://www.sciencedaily.com/releases/2012/06/120613102130.htmhttp://www.sciencedaily.com/releases/2012/06/120612145139.htm Researchers have created a computational tool to help predict how proteins fold by finding amino acid pairs that are distant in sequence but change together. Protein interactions offer clues to the treatment of disease, including cancer.Tue, 12 Jun 2012 14:51:51 EDThttp://www.sciencedaily.com/releases/2012/06/120612145139.htmhttp://www.sciencedaily.com/releases/2012/06/120612101458.htm A novel porous material that has unique carbon dioxide retention properties has just been developed.Tue, 12 Jun 2012 10:14:14 EDThttp://www.sciencedaily.com/releases/2012/06/120612101458.htmhttp://www.sciencedaily.com/releases/2012/06/120611193636.htm A newly developed carbon nanotube material could help lower the cost of fuel cells, catalytic converters and similar energy-related technologies by delivering a substitute for expensive platinum catalysts.Mon, 11 Jun 2012 19:36:36 EDThttp://www.sciencedaily.com/releases/2012/06/120611193636.htmhttp://www.sciencedaily.com/releases/2012/06/120611105311.htm New groundbreaking research has found that exposure to nanoparticles can have a serious impact on health, linking it to rheumatoid arthritis and the development of other serious autoimmune diseases. The findings have health and safety implications for the manufacture, use and ultimate disposal of nanotechnology products and materials. They also identified new cellular targets for the development of potential drug therapies in combating the development of autoimmune diseases.Mon, 11 Jun 2012 10:53:53 EDThttp://www.sciencedaily.com/releases/2012/06/120611105311.htmhttp://www.sciencedaily.com/releases/2012/06/120611092345.htm Researchers have created a reliable and fast flu-detection test that can be carried in a first-aid kit. The novel prototype device isolates influenza RNA using a combination of magnetics and microfluidics, then amplifies and detects probes bound to the RNA. The technology could lead to real-time tracking of influenza.Mon, 11 Jun 2012 09:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120611092345.htmhttp://www.sciencedaily.com/releases/2012/06/120610151304.htm Enabling bioengineers to design new molecular machines for nanotechnology applications is one of the possible outcomes of a new study. Scientists have developed a new approach to visualize how proteins assemble, which may also significantly aid our understanding of diseases such as Alzheimer's and Parkinson's, which are caused by errors in assembly.Sun, 10 Jun 2012 15:13:13 EDThttp://www.sciencedaily.com/releases/2012/06/120610151304.htmhttp://www.sciencedaily.com/releases/2012/06/120606155808.htm Using ultrafast, intensely bright pulses of X-rays scientists have obtained the first ever images at room temperature of photosystem II, a protein complex critical for photosynthesis and future artificial photosynthetic systems.Wed, 06 Jun 2012 15:58:58 EDThttp://www.sciencedaily.com/releases/2012/06/120606155808.htmhttp://www.sciencedaily.com/releases/2012/06/120606132316.htm A new voyage into "chemical space" ? occupied not by stars and planets but substances that could become useful in everyday life ? has concluded that scientists have synthesized barely one tenth of one percent of potential medicines. The report estimates that the actual number of these so-called "small molecules" could be one novemdecillion (that's one with 60 zeroes), more than some estimates of the number of stars in the universe.Wed, 06 Jun 2012 13:23:23 EDThttp://www.sciencedaily.com/releases/2012/06/120606132316.htmhttp://www.sciencedaily.com/releases/2012/06/120605121639.htm Halogens particularly chlorine, bromine, and iodine ? have a unique quality which allows them to positively influence the interaction between molecules. This ?halogen bonding? has been employed in the area of materials science for some time, but is only now finding applications in the life sciences.Tue, 05 Jun 2012 12:16:16 EDThttp://www.sciencedaily.com/releases/2012/06/120605121639.htmhttp://www.sciencedaily.com/releases/2012/06/120605102842.htm Researchers have developed a highly sensitive detector of infrared light that can be used in applications ranging from detection of chemical and biochemical weapons from a distance and better airport body scanners to chemical analysis in the laboratory and studying the structure of the universe through new telescopes.Tue, 05 Jun 2012 10:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120605102842.htmhttp://www.sciencedaily.com/releases/2012/06/120604092858.htm A new microscope enabled scientists to film a fruit fly embryo, in 3D, from when it was about two-and-a-half hours old until it walked away from the microscope as a larva.Mon, 04 Jun 2012 09:28:28 EDThttp://www.sciencedaily.com/releases/2012/06/120604092858.htmhttp://www.sciencedaily.com/releases/2012/06/120603191722.htm A new study suggests that the replication process for DNA -- the genetic instructions for living organisms that is composed of four bases (C, G, A and T) -- is more open to unnatural letters than had previously been thought. An expanded "DNA alphabet" could carry more information than natural DNA, potentially coding for a much wider range of molecules and enabling a variety of powerful applications, from precise molecular probes and nanomachines to useful new life forms.Sun, 03 Jun 2012 19:17:17 EDThttp://www.sciencedaily.com/releases/2012/06/120603191722.htmhttp://www.sciencedaily.com/releases/2012/05/120531165752.htm A laboratory test used to detect disease and perform biological research could be made more than 3 million times more sensitive, according to researchers who combined standard biological tools with a breakthrough in nanotechnology.Thu, 31 May 2012 16:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531165752.htmhttp://www.sciencedaily.com/releases/2012/05/120531145728.htm Scientists have demonstrated how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical new investigative avenues in biology.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145728.htmhttp://www.sciencedaily.com/releases/2012/05/120531145720.htm Biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the first step toward developing new methods of drug delivery or even designing artificial vaccines.Thu, 31 May 2012 14:57:57 EDThttp://www.sciencedaily.com/releases/2012/05/120531145720.htmhttp://www.sciencedaily.com/releases/2012/05/120531145630.htm Ultrashort flashes of X-radiation allow atomic structures of macromolecules to be obtained even from tiny protein crystals.Thu, 31 May 2012 14:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120531145630.htmhttp://www.sciencedaily.com/releases/2012/05/120531102207.htm Our ability to "read" DNA has made tremendous progress in the past few decades, but the ability to understand and alter the genetic code, that is, to "rewrite" the DNA-encoded instructions, has lagged behind. A new study advances our understanding of the genetic code: It proposes a way of effectively introducing numerous carefully planned DNA segments into genomes of living cells and of testing the effects of these changes. New technology speeds up DNA "rewriting" and measures the effects of the changes in living cells.Thu, 31 May 2012 10:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120531102207.htmhttp://www.sciencedaily.com/releases/2012/05/120530152203.htm Researchers have developed a method for building complex nanostructures out of interlocking DNA "building blocks" that can be programmed to assemble themselves into precisely designed shapes. With further development, the technology could one day enable the creation of new nanoscale devices that deliver drugs directly to disease sites.Wed, 30 May 2012 15:22:22 EDThttp://www.sciencedaily.com/releases/2012/05/120530152203.htmhttp://www.sciencedaily.com/releases/2012/05/120530104034.htm Inexpensive, portable devices that can rapidly screen cells for leukemia or HIV may soon be possible thanks to a chip that can produce three-dimensional focusing of a stream of cells, according to researchers.Wed, 30 May 2012 10:40:40 EDThttp://www.sciencedaily.com/releases/2012/05/120530104034.htmhttp://www.sciencedaily.com/releases/2012/05/120530100041.htm Scientists have engineered cells that behave like AND and OR Boolean logic gates, producing an output based on one or more unique inputs. This feat could eventually help researchers create computers that use cells as tiny circuits.Wed, 30 May 2012 10:00:00 EDThttp://www.sciencedaily.com/releases/2012/05/120530100041.htmhttp://www.sciencedaily.com/releases/2012/05/120529113543.htm An integrated chemical chip has just been developed. An advantage of chemical circuits is that the charge carrier consists of chemical substances with various functions. This means that we now have new opportunities to control and regulate the signal paths of cells in the human body. The chemical chip can control the delivery of the neurotransmitter acetylcholine. This enables chemical control of muscles, which are activated when they come into contact with acetylcholine.Tue, 29 May 2012 11:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120529113543.htmhttp://www.sciencedaily.com/releases/2012/05/120528154859.htm Physicists have developed a method that models biological cell-to-cell adhesion that could also have industrial applications.Mon, 28 May 2012 15:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120528154859.htmhttp://www.sciencedaily.com/releases/2012/05/120528100253.htm Scientists have created and imaged the smallest possible five-ringed structure -- about 100,000 times thinner than a human hair. Dubbed 'olympicene', the single molecule was brought to life in a picture thanks to a combination of clever synthetic chemistry and state-of-the-art imaging techniques.Mon, 28 May 2012 10:02:02 EDThttp://www.sciencedaily.com/releases/2012/05/120528100253.htmhttp://www.sciencedaily.com/releases/2012/05/120527153818.htm Multi-walled carbon nanotubes riddled with defects and impurities on the outside could replace some of the expensive platinum catalysts used in fuel cells and metal-air batteries, according to scientists.Sun, 27 May 2012 15:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120527153818.htmhttp://www.sciencedaily.com/releases/2012/05/120527153718.htm Scientists have developed an ultra-sensitive test that should enable them to detect signs of a disease in its earliest stages.Sun, 27 May 2012 15:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120527153718.htmhttp://www.sciencedaily.com/releases/2012/05/120525103614.htm Images of the cell's transport pods have revealed a molecular version of the robots from Transformers. Previously, scientists had been able to create and determine the structure of 'cages' formed by parts of the protein coats that encase other types of vesicles, but this study was the first to obtain high-resolution images of complete vesicles, budded from a membrane.Fri, 25 May 2012 10:36:36 EDThttp://www.sciencedaily.com/releases/2012/05/120525103614.htmhttp://www.sciencedaily.com/releases/2012/05/120524143527.htm There's nothing like a new pair of eyeglasses to bring fine details into sharp relief. For scientists who study the large molecules of life from proteins to DNA, the equivalent of new lenses have come in the form of an advanced method for analyzing data from X-ray crystallography experiments.Thu, 24 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120524143527.htmhttp://www.sciencedaily.com/releases/2012/05/120524123232.htm Researchers are using nanoparticles to simultaneously deliver proteins and DNA into plant cells. The technology could allow more sophisticated and targeted editing of plant genomes. And that could help researchers develop crops that adapt to changing climates and resist pests.Thu, 24 May 2012 12:32:32 EDThttp://www.sciencedaily.com/releases/2012/05/120524123232.htmhttp://www.sciencedaily.com/releases/2012/05/120524092932.htm Quantum physics and plant biology seem like two branches of science that could not be more different, but surprisingly they may in fact be intimately tied. Scientists have discovered an unusual quantum effect in the earliest stages of photosynthesis.Thu, 24 May 2012 09:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120524092932.htmhttp://www.sciencedaily.com/releases/2012/05/120523135527.htm Quantum computers may someday revolutionize the information world. But in order for quantum computers at distant locations to communicate with one another, they have to be linked together in a network. While several building blocks for a quantum computer have already been successfully tested in the laboratory, a network requires one additonal component: A reliable interface between computers and information channels. Austrian physicists now report the construction of an efficient and tunable interface for quantum networks.Wed, 23 May 2012 13:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120523135527.htmhttp://www.sciencedaily.com/releases/2012/05/120522152655.htm Rapid DNA sequencing may soon become a routine part of each individual's medical record, providing enormous information previously sequestered in the human genome's 3 billion nucleotide bases. Recent advances in sequencing technology using a tiny orifice known as a nanopore are covered in a new a article.Tue, 22 May 2012 15:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120522152655.htmhttp://www.sciencedaily.com/releases/2012/05/120521164104.htm Scientists have synthesized polymers to attach to proteins in order to stabilize them during shipping, storage and other activities. The study findings suggest that these polymers could be useful in stabilizing protein formulations.Mon, 21 May 2012 16:41:41 EDThttp://www.sciencedaily.com/releases/2012/05/120521164104.htmhttp://www.sciencedaily.com/releases/2012/05/120521163751.htm Scientists have devised a method for repeatedly encoding, storing and erasing digital data within the DNA of living cells. In practical terms, they have devised the genetic equivalent of a binary digit -- a "bit" in data parlance.Mon, 21 May 2012 16:37:37 EDThttp://www.sciencedaily.com/releases/2012/05/120521163751.htmhttp://www.sciencedaily.com/releases/2012/05/120521115654.htm Blood tests convey vital medical information, but the sight of a needle often causes anxiety and results take time. A new device however, can reveal much the same information as a traditional blood test in real-time, simply by shining a light through the skin. This portable optical instrument is able to provide high-resolution images of blood coursing through veins without the need for harsh fluorescent dyes.Mon, 21 May 2012 11:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120521115654.htmhttp://www.sciencedaily.com/releases/2012/05/120521103808.htm The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers have now elucidated the structure of such a needle at atomic resolution. Their findings might contribute to drug tailoring and the development of strategies which specifically prevent the infection process.Mon, 21 May 2012 10:38:38 EDThttp://www.sciencedaily.com/releases/2012/05/120521103808.htmhttp://www.sciencedaily.com/releases/2012/05/120518132657.htm Tiny beads may act as minimally invasive glucose sensors for a variety of applications in cell culture systems and tissue engineering.Fri, 18 May 2012 13:26:26 EDThttp://www.sciencedaily.com/releases/2012/05/120518132657.htmhttp://www.sciencedaily.com/releases/2012/05/120518081147.htm Using newly developed imaging technology, chemists have confirmed years of theoretical assumptions about water molecules, the most abundant and one of the most frequently studied substances on Earth.Fri, 18 May 2012 08:11:11 EDThttp://www.sciencedaily.com/releases/2012/05/120518081147.htmhttp://www.sciencedaily.com/releases/2012/05/120517193141.htm Researchers have come closer to solving an old challenge of producing graphene quantum dots of controlled shape and size at large densities, which could revolutionize electronics and optoelectronics.Thu, 17 May 2012 19:31:31 EDThttp://www.sciencedaily.com/releases/2012/05/120517193141.htmhttp://www.sciencedaily.com/releases/2012/05/120517143506.htm Scientists have discovered how adding trace amounts of water can tremendously speed up chemical reactions -? such as hydrogenation and hydrogenolysis ?- in which hydrogen is one of the reactants, or starting materials.Thu, 17 May 2012 14:35:35 EDThttp://www.sciencedaily.com/releases/2012/05/120517143506.htmhttp://www.sciencedaily.com/releases/2012/05/120514104848.htm Three proteins have been found to be involved in the accumulation of fatty acids in plants. The discovery could help plant scientists boost seed oil production in crops. And that could boost the production of biorenewable fuels and chemicals.Mon, 14 May 2012 10:48:48 EDThttp://www.sciencedaily.com/releases/2012/05/120514104848.htmhttp://www.sciencedaily.com/releases/2012/05/120510095622.htm A new approach to generating terahertz radiation will lead to new imaging and sensing applications. The low energy of the radiation means that it can pass through materials that are otherwise opaque, opening up uses in imaging and sensing ? for example, in new security scanners. In practice, however, applications have been difficult to implement.Thu, 10 May 2012 09:56:56 EDThttp://www.sciencedaily.com/releases/2012/05/120510095622.htmhttp://www.sciencedaily.com/releases/2012/05/120509135959.htm To better understand how microRNAs -- small pieces of genetic material -- influence human health and disease, scientists first need to know which microRNAs act upon which genes. To do this scientists developed miR-TRAP, a new easy-to-use method to directly identify microRNA targets in cells.Wed, 09 May 2012 13:59:59 EDThttp://www.sciencedaily.com/releases/2012/05/120509135959.htmhttp://www.sciencedaily.com/releases/2012/05/120508173349.htm Researchers have boosted the efficiency of a novel source of white light called quantum dots more than tenfold, making them of potential interest for commercial applications.Tue, 08 May 2012 17:33:33 EDThttp://www.sciencedaily.com/releases/2012/05/120508173349.htmhttp://www.sciencedaily.com/releases/2012/05/120508152129.htm Chemists have designed a molecular container that can hold drug molecules and increase their solubility, in one case up to nearly 3,000 times.Tue, 08 May 2012 15:21:21 EDThttp://www.sciencedaily.com/releases/2012/05/120508152129.htmhttp://www.sciencedaily.com/releases/2012/05/120503194229.htm Researchers have developed a prototype bioreactor that both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis.Thu, 03 May 2012 19:42:42 EDThttp://www.sciencedaily.com/releases/2012/05/120503194229.htmhttp://www.sciencedaily.com/releases/2012/05/120503120130.htm A new technique predictably generates complex, wavy shapes and may help improve drug delivery and explain natural patterns from brain folds to bell peppers.Thu, 03 May 2012 12:01:01 EDThttp://www.sciencedaily.com/releases/2012/05/120503120130.htmhttp://www.sciencedaily.com/releases/2012/05/120502132953.htm Liquid crystals, the state of matter that makes possible the flat screen technology now commonly used in televisions and computers, may have some new technological tricks in store.Wed, 02 May 2012 13:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502132953.htmhttp://www.sciencedaily.com/releases/2012/05/120502112910.htm A new nanotube super sensor is able to detect subtle differences with a single sniff. For example, the chemical dimethylsulfone is associated with skin cancer. The human nose cannot detect this volatile but it could be detected with the new sensor at concentrations as low as 25 parts per billion.Wed, 02 May 2012 11:29:29 EDThttp://www.sciencedaily.com/releases/2012/05/120502112910.htmhttp://www.sciencedaily.com/releases/2012/05/120502091839.htm A new biomimetic approach to synthesising polymers will offer unprecedented control over the final polymer structure and yield advances in nanomedicine, researchers say.Wed, 02 May 2012 09:18:18 EDThttp://www.sciencedaily.com/releases/2012/05/120502091839.htmhttp://www.sciencedaily.com/releases/2012/05/120501085502.htm Scientists using high-powered microscopes have made a stunning observation of the architecture within a cell ? and identified for the first time how the architecture changes during the formation of gametes, also known as sex cells, in order to successfully complete? the process.Tue, 01 May 2012 08:55:55 EDThttp://www.sciencedaily.com/releases/2012/05/120501085502.htmhttp://www.sciencedaily.com/releases/2012/04/120430151752.htm Biomedical engineers have demonstrated the first all-polymeric bone scaffold that is fully biodegradable and offers significant mechanical support during repair. The technique uses silk fibers to reinforce a silk matrix. Adding microfibers to the scaffolds enhances bone formation and mechanical properties. It could improve repair after accident or disease.Mon, 30 Apr 2012 15:17:17 EDThttp://www.sciencedaily.com/releases/2012/04/120430151752.htmhttp://www.sciencedaily.com/releases/2012/04/120430114937.htm Cells regulate their functions by adding or subtracting phosphates from proteins. If scientists could study the process in detail, in individual cells over time, understanding and treating diseases would be greatly aided. Formerly this was impossible without damaging the cells or interfering with the process itself, but scientists have now achieved the goal by using bright infrared beams and a technique called Fourier transform spectromicroscopy.Mon, 30 Apr 2012 11:49:49 EDThttp://www.sciencedaily.com/releases/2012/04/120430114937.htm

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2 Alaska troopers shot, gunman found dead

ANCHORAGE, Alaska (AP) ? Two Alaska State Troopers were shot Sunday in a remote town north of the Arctic Circle and a near-nine hour standoff with a gunman ended with the suspect apparently taking his own life, authorities said.

Law officers found Arvid Nelson Jr. about 6 p.m. Sunday in his pickup truck, dead of an apparent self-inflicted gunshot wound, State Troopers spokeswoman Beth Ipsen said.

In gunfire that led to the standoff, one of the troopers was seriously wounded and flown to Anchorage, 550 miles southeast. The other was less seriously injured and treated locally.

Ipsen said Nelson was from Kotzebue, which serves as a regional hub for Inupiat Eskimo villages, but no other details about him were released, including his age.

The standoff began around 9 a.m. after troopers responded to a report of shots possibly fired. As troopers approached Nelson's pickup truck, shooting erupted that left the two injured, authorities said.

A Trooper statement shed no light on what prompted Nelson to remain holed up in his truck for the next several hours.

City Attorney Joe Evans witnessed the initial shooting and said the incident began as he was having breakfast with police Chief Craig Moates.

Moates took a call that there may have been shots fired from a man in a pickup truck toward a police officer in a patrol car and Evans accompanied the chief to where the pickup had crashed into a guardrail.

By that time, Evans said, three patrol cars had arrived carrying two Kotzebue police officers and the two state troopers. Evans and the chief observed from 75 to 100 yards away, expecting a quick resolution.

"When I arrived, I thought nothing else was going to happen," Evans said.

With a Kotzebue officer driving a patrol car, at least two officers on foot approached the pickup. The officers on foot were shielded by the open front doors of the patrol car. Evans said there may have been two officers walking on the driver's side plus one on the passenger side.

The patrol car drove about 1 mph, he said, and when it was about 15 yards from the pickup, shots rang out. A trooper behind the driver's side door crumpled to the ground.

The other officers came to his assistance and placed the wounded man in the car. The patrol car backed up with the wounded man inside.

At least one officer returned fire but it's unknown whether the suspect was struck, Ipsen said.

The others officers gathered near the chief's car, Evans said. The second trooper said his head hurt, Evans said, and when he took off his cap, he noticed he was bleeding.

"There was a track across his head," Evans said.

The trooper had suffered either a graze from a bullet or possibly, shrapnel from a piece of a bullet off a ricochet, Evans said. The trooper at first declined treatment but then drove to the clinic. He also escorted Evans from the scene.

The Kotzebue airport was shut down to non-emergency traffic because the pickup was near the end of the runway, Ipsen said.

Associated Press

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Hammel's 1-hitter lifts O's past Braves

By GEORGE HENRY

Associated Press

Associated Press Sports

updated 10:16 p.m. ET June 16, 2012

ATLANTA (AP) - Jason Hammel just wanted go deep into the game and give Baltimore's bullpen some rest.

He nearly got his first no-hitter in the process.

Hammel pitched a one-hitter for his first career shutout, allowing only Jason Heyward's two-out single in the seventh inning, and the Orioles beat the Atlanta Braves 5-0 on Saturday night.

"A no-hitter would've been nice, but it gave the bullpen the night off," Hammel said. "I heard from them. Not one bullpen pitch thrown. That's huge because we've been taxing them pretty good."

There have already been five no-hitters in the majors this season, including three this month, and Hammel made a strong bid to add to the list. He struck out eight and walked two, throwing 65 of 102 pitches for strikes.

Brian Roberts drove in three runs for the Orioles, who have won six of seven.

Atlanta pitcher Brandon Beachy (5-5) left in the fourth inning with right elbow soreness. The major leagues' ERA leader allowed no hits and one run, struck out five and walked one.

The Braves have lost five of six.

Hammel (7-2) had been struggling on the road, entering with a 1-1 record and a 4.76 ERA in his previous three starts away from Camden Yards. But he settled down after walking Dan Uggla on four pitches to begin the second.

Hammel retired the next 17 batters he faced before walking Uggla again with two out in the seventh. Heyward followed with a clean single to left field, but Eric Hinske flied out to end the inning.

Hammel got through the ninth in six pitches, retiring Michael Bourn on a flyout and Martin Prado and Brian McCann on groundouts before receiving congratulations from his teammates.

The Baltimore dugout started buzzing as Hammel ended the fifth with a no-hitter intact.

"A lot of guys get in a different mental frame, but you could tell that he didn't," Orioles manager Buck Showalter said. "I think everybody kind of knew what was going on. Guys were starting to scatter in the dugout, and I noticed guys standing in the same place, including me."

Acquired in the February trade that sent Jeremy Guthrie to Colorado, Hammel had pitched poorly against Atlanta before Saturday, going 0-3 with 9.00 ERA in five career starts overall and 0-2 with a 11.74 ERA in two starts at Turner Field.

"I had a terrible track record against the Braves," Hammel said. "These guys have given me nightmares, especially here at Turner Field. I'm very excited to get out of here with a win. They put a good team on the field every year."

After walking Chris Davis on six pitches with two outs in the fourth, Beachy stopped in front of the mound and signaled to catcher Brian McCann that he was injured. He walked off the field during a mound visit from manager Fredi Gonzalez.

Beachy, who made 40 of his 57 pitches for strikes, retired his first 11 batters. He now has a 2.00 ERA.

"We're going to get the MRI and hope for the best on the results," Beachy said. "It's really frustrating. I've had a lot of success when I've felt good this year. I feel like I'm in a position where I know more. I know what I'm trying to do and I'm doing it, when I physically can."

Anthony Varvaro came in and walked Adam Jones and Matt Wieters to load the bases. Mark Reynolds then hit a two-run single to give the Orioles a 2-0 lead.

Baltimore went ahead 3-0 in the fifth when Roberts' single off Varvaro scored Steve Pearce from second.

Cristhian Martinez, the third Atlanta pitcher, worked a scoreless sixth before Roberts lined a two-run single to right.

Hammel, who took a no-hitter into the eighth inning April 8 before beating the Minnesota Twins 3-1, said his bullpen session gave him no idea he would one-hit the Braves.

"I actually had a terrible bullpen, believe it or not," he said. "I was kind of feeling my way through the first two innings and then obviously just carried it on and found a pretty good groove."

NOTES: It was Hammel's second career complete game and first since he pitched eight innings in the Rockies' 1-0 loss at the Los Angeles Dodgers on July 1, 2009. ... Bourn went 0 for 4 to snap a career-high 14-game hitting streak. ... Gonzalez said before the game that Chipper Jones, who was held out with a swollen left knee, will be in the lineup at 3B on Sunday. ... Gonzalez likely will use Jones as a designated hitter when Atlanta visits the New York Yankees and Boston Red Sox next week. ... Atlanta 1B Freddie Freeman was out of the lineup with a swollen knuckle on his left index finger. ... Showalter said RF Nick Markakis, who underwent right wrist surgery on June 1, will visit a doctor on Friday for a standard checkup. Markakis was initially expected to miss three to four weeks. ... Roberts is expected to get a standard day off Sunday with 2B Robert Andino starting in his place.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Mark Teixeira hit a two-run double in the 14th inning Saturday as the New York Yankees won their eighth straight game, beating the Washington Nationals 5-3.

Hammel's 1-hitter lifts O's past Braves

ATLANTA (AP) - Jason Hammel pitched a one-hitter for his first career shutout, allowing only Jason Heyward's two-out single in the seventh inning, and the Baltimore Orioles beat the Atlanta Braves 5-0 on Saturday night.

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'realMyst' Sees A Release On iPad 2 And New iPad

Touch Arcade writes, realMyst [$6.99] for iPad -- which is now actually called just realMyst -- is available on the App Store today as promised, and it's rocking a $6.99 price tag. realMyst includes all of the content from the original Myst plus "Rime Age," and includes a few hip features like save states, auto-saves, and a hint book. realMyst is a port of a re-release of Myst that, for the first time, gave Myst fans that ability to explore the original game in 3D. This version includes dynamic water and environmental effects, too. Early word from our message board seems to be positive, but we'll be digging in soon, too. Stay tuned. App Store Link: realMyst, $6.99 (iPad Only)

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'Mad Men' Fans Angered By Slate Writer, Tom Scocca's Assertion Don Draper Does Not Exist

Bad news for "Mad Men" fans who thought they were watching a five-season documentary -- Don Draper is not a real person. We know, we know -- your mind has been blown.

On June 8, Tom Scocca's Slate article, "Don Draper?s Shocking Secret: He Doesn?t Exist," blew the lid off that secret for good, and managed to anger some of the show's fans.

Twitter user Eric Thurm called the article "one of the most condescending things" he'd ever read, while Dov Friedman, called it "aggressively awful."

In the article, Scocca explains that "Don Draper is a made-up person inside your television set. He is a pattern of lit-up dots moving in front of your eyes for one hour, on Sundays, during the season run of the Mad Men program, which mercifully ends this weekend."

Though viewers of the AMC drama are more than aware that Draper, his family and advertising company Sterling Cooper Draper Pryce are all born out of the mind of the show's creator Matt Weiner, Scocca is not convinced because of how often the show is referenced in the news. He says he is perplexed by how often other writers have chosen to use a pop culture reference to help explain a concept or event.

"What's wrong with 'Mad Men' isn't that it makes you boring. What's wrong with 'Mad Men' is that it also makes you stupid," he wrote, before listing an excerpt from a 2011 column in the business section of The New York Times:

As more and more women have come into the work force, corporate America has made significant, if agonizingly slow, progress in making sure its attitudes and the conduct of its leadership reflect those changes. It's no longer a ''Mad Men'' world where women are expected to fetch coffee and whiskey and service their bosses in other ways.

Much to Scocca's chagrin, "Mad Men" has become synonymous with the '60s and Don Draper its foremost figure -- but what he's really angry about his the fact that fans and writers won't shut up about it.

After listing five articles that reference the show he explains:

"What's remarkable -- almost miraculous -- about these 'Mad Men' references is how universally, completely meaningless they are. I belong to the 99 percent of the American public that does not watch 'Mad Men,' yet there's nothing about the Don Draper comparisons that is lost on me."

It's true "Mad Men" is not the country's most watched program -- that title belongs to NBC's Sunday Night Football, which averaged 20.7 million viewers each game this season. But no one seemed to explain to Scocca that a football analogy doesn't quite work when writing about slow changes to the sexist attitudes in corporate America.

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